There is a new paper in Fertility and Sterility (Fertil Steril. 2012 Aug 7. [Epub ahead of print) in that offers an excellent review of the mechanism of action of chlamydia on the Fallopian tube – what we know and where the gaps are in our knowledge. It is a review of the literature – so rather than summarise the paper here – we advise you to read it where is can be accessed on PUBmed.
The paper outlines how complex the mechanisms are that can lead to tubal infertility. It also describes how knockout mouse models can be used to study tubal function in the hope of better understanding how chlamydia impacts on tubal motility and implantation .